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Phase Ib Clinical Trial of Autologous Anti-NY-ESO-1 TCR-Engineered T Cells in Patients With Relapsed/Refractory Locally Advanced or Metastatic NY-ESO-1-Expressing Triple Negative Breast Cancer

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Trial Profile

Phase Ib Clinical Trial of Autologous Anti-NY-ESO-1 TCR-Engineered T Cells in Patients With Relapsed/Refractory Locally Advanced or Metastatic NY-ESO-1-Expressing Triple Negative Breast Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Jul 2025

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At a glance

  • Drugs Aldesleukin (Primary) ; Cyclophosphamide (Primary) ; Fludarabine (Primary) ; NY-ESO-1 TCR-T cell therapy (Primary)
  • Indications Advanced breast cancer; Triple negative breast cancer
  • Focus Adverse reactions

Most Recent Events

  • 01 Jan 2025 Planned End Date changed from 1 Oct 2027 to 17 Dec 2027.
  • 01 Jan 2025 Planned primary completion date changed from 1 Oct 2026 to 17 Dec 2026.
  • 01 Jan 2025 Status changed from not yet recruiting to recruiting.

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