Trial Profile

A Randomized, Partially Observer-blind, Dose-escalation, Phase I/II Trial Evaluating the Safety and Immunogenicity of Investigational RNA-based Mpox Vaccine Candidates

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 01 Apr 2026

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At a glance

Drugs BNT 166a (Primary) ; BNT 166c (Primary)
Indications Monkeypox
Focus Adverse reactions
Sponsors BioNTech

Most Recent Events

27 Mar 2026 Status changed from active, no longer recruiting to completed.
22 Oct 2025 Actual primary completion date changed to 25 Aug 2025.
13 Mar 2025 Status changed from recruiting to active, no longer recruiting.

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