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A Randomized, Partially Observer-blind, Dose-escalation, Phase I/II Trial Evaluating the Safety and Immunogenicity of Investigational RNA-based Mpox Vaccine Candidates

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A Randomized, Partially Observer-blind, Dose-escalation, Phase I/II Trial Evaluating the Safety and Immunogenicity of Investigational RNA-based Mpox Vaccine Candidates

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 17 Mar 2025

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At a glance

  • Drugs BNT 166a (Primary) ; BNT 166c (Primary)
  • Indications Monkeypox
  • Focus Adverse reactions
  • Sponsors BioNTech

    • Most Recent Events

    • 13 Mar 2025 Status changed from recruiting to active, no longer recruiting.
    • 03 Dec 2024 Planned number of patients changed from 64 to 96.
    • 03 Dec 2024 Status changed to recruiting.

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