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Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

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Trial Profile

Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 14 Oct 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; PRGN-2009 (Primary)
  • Indications Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use

Most Recent Events

  • 03 Oct 2025 Planned End Date changed from 1 Nov 2028 to 16 Jul 2030.
  • 03 Oct 2025 Status changed from recruiting to active, no longer recruiting.
  • 14 Nov 2024 Planned End Date changed from 1 Nov 2027 to 1 Nov 2028.

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