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A Randomised, Placebo-Controlled, Dose-Ranging, Observer-Blind Phase 1/2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of mRNA-1769 in Healthy Participants

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Trial Profile

A Randomised, Placebo-Controlled, Dose-Ranging, Observer-Blind Phase 1/2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of mRNA-1769 in Healthy Participants

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 29 Jul 2025

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At a glance

  • Drugs MRNA-1769 (Primary)
  • Indications Monkeypox; Smallpox
  • Focus Adverse reactions
  • Sponsors Moderna Therapeutics

Most Recent Events

  • 16 Jul 2025 Status changed from active, no longer recruiting to completed.
  • 18 Jun 2025 Planned End Date changed from 13 Jun 2025 to 3 Jul 2025.
  • 18 Jun 2025 Planned primary completion date changed from 13 Jun 2025 to 3 Jul 2025.

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