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A Phase I/II Study of the JAK1/2 Inhibitor Ruxolitinib for Relapsed / Refractory Immune Bone Marrow Failure

Trial Profile

A Phase I/II Study of the JAK1/2 Inhibitor Ruxolitinib for Relapsed / Refractory Immune Bone Marrow Failure

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 02 Apr 2025

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At a glance

  • Drugs Ruxolitinib (Primary)
  • Indications Anaemia; Aplastic anaemia; Bone marrow aplasia; Bone marrow disorders; Febrile neutropenia; Large granular lymphocytic leukaemia; Myelodysplastic syndromes; Neutropenia; Pure red cell aplasia; Thrombocytopenia
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 10 Dec 2024 Study Design and Methods, presented at the 66th American Society of Hematology Annual Meeting and Exposition
  • 21 Feb 2024 Planned initiation date (estimated date for recruitment of the first subject) changed to 27 Feb 2024.
  • 25 Jan 2024 Planned initiation date (estimated date for recruitment of the first subject) changed from 29 Jan 2024 to 5 Feb 2024.

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