Trial Profile

A Phase 2, Randomized, Active-Controlled, Open-Label Study to Evaluate the Efficacy and Safety of LBL-007 in Combination With Tislelizumab Plus Chemotherapy as First-Line Treatment in Patients With Unresectable Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 28 May 2025

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At a glance

Drugs LBL-007 (Primary) ; Tislelizumab (Primary) ; Cisplatin; Fluorouracil; Paclitaxel
Indications Carcinoma; Oesophageal cancer; Squamous cell cancer
Focus Therapeutic Use
Sponsors BeOne Medicines

22 May 2025 Planned End Date changed from 1 Sep 2025 to 23 May 2026.
30 May 2024 Status changed from recruiting to active, no longer recruiting.
10 Apr 2024 Trial design presented at the 115th Annual Meeting of the American Association for Cancer Research.

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