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An Open-Label Phase I Study With an Expansion Cohort of JAK Inhibitor Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

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An Open-Label Phase I Study With an Expansion Cohort of JAK Inhibitor Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 23 Dec 2024

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At a glance

  • Drugs Ruxolitinib (Primary)
  • Indications Acute myeloid leukaemia; Cytokine release syndrome; Graft-versus-host disease; Myelodysplastic syndromes; Myelofibrosis; Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use

    • Most Recent Events

    • 07 May 2024 Planned End Date changed from 11 Nov 2026 to 11 Dec 2026.
    • 07 May 2024 Planned primary completion date changed from 9 Aug 2026 to 9 Sep 2026.
    • 07 May 2024 Status changed from not yet recruiting to recruiting.

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