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A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of PF-08052666/SGN-MesoC2 in Participants With Advanced Solid Tumors

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Trial Profile

A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of PF-08052666/SGN-MesoC2 in Participants With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Jun 2025

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At a glance

  • Drugs HBM-9033 (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Colorectal cancer; Lung cancer; Mesothelioma; Ovarian cancer; Pancreatic cancer; Pancreatic ductal carcinoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Harbour BioMed; Seagen

Most Recent Events

  • 19 Jun 2025 Planned End Date changed from 16 Feb 2029 to 1 May 2029.
  • 19 Jun 2025 Planned primary completion date changed from 17 Feb 2028 to 1 May 2028.
  • 23 May 2025 According to a Nona Biosciences media release, data from this study will be presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.

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