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A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced/Metastatic Solid Tumors

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Trial Profile

A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of HLX43 (Anti-PD-L1 ADC) in Patients With Advanced/Metastatic Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Jun 2025

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At a glance

  • Drugs HLX 43 (Primary)
  • Indications Cervical cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Henlius Biopharmaceuticals

Most Recent Events

  • 10 Jun 2025 According to a Shanghai Henlius Biotech media release, results form this phase I trial were presented at the 2025 ASCO Annual Meeting and ESMO congress 2025.
  • 31 May 2025 Planned number of patients changed from 36 to 174.
  • 15 May 2025 Planned End Date changed from 30 Nov 2025 to 30 Nov 2027.

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