An Interventional, Prospective Open-Label Study of Immunosuppressive Therapies to Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)
Latest Information Update: 03 Feb 2025
At a glance
- Drugs Asfotase alfa (Primary) ; Bortezomib (Primary) ; Bortezomib (Primary) ; Folic acid (Primary) ; Methotrexate (Primary) ; Methotrexate (Primary) ; Rituximab (Primary)
- Indications Hypophosphatasia
- Focus Therapeutic Use
- Acronyms RESTORE
- Sponsors Alexion AstraZeneca Rare Disease
- 29 Jan 2025 Planned End Date changed from 15 Jan 2029 to 14 Feb 2029.
- 29 Jan 2025 Planned primary completion date changed from 15 Jan 2029 to 14 Feb 2029.
- 29 Jan 2025 Planned initiation date changed from 15 Jan 2025 to 2 Jul 2025.