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A multi-center Phase 2 study of neoadjuvant immunotherapy in combination with the anti-GDF-15 antibody visugromab (CTL-002) for the treatment of muscle invasive bladder cancer

Trial Profile

A multi-center Phase 2 study of neoadjuvant immunotherapy in combination with the anti-GDF-15 antibody visugromab (CTL-002) for the treatment of muscle invasive bladder cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 17 Nov 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Visugromab (Primary)
  • Indications Bladder cancer; Carcinoma
  • Focus Therapeutic Use
  • Acronyms GDFather-Neo; NEO-GDFATHER
  • Sponsors CatalYm

Most Recent Events

  • 17 Oct 2025 According to a CatalYm media release, the data from this trial was presented today by the trials Principal Investigator, Prof. Dr. Andrea Necchi, as an oral late-breaker at the ESMO Congress 2025
  • 17 Oct 2025 Results published in the CatalYm Media Release
  • 22 Sep 2025 According to a CatalYm media release, today announced upcoming oral presentations highlighting data from this trial to be presented at the European Society of Medical Oncology (ESMO) Congress, being held October 17th-21st, 2025, in Berlin, Germany.

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