Trial Profile

A Phase 1/2 Single-center Study Evaluating the Safety and Efficacy of TRAC and Power3 Genes Knock-out Allogeneic CD19-targeting CAR-T Cell (ATHENA) Therapy in Adults With Refractory/Relapsed B-cell Non-Hodgkin Lymphoma

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 19 Feb 2025

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At a glance

Drugs ET 901 (Primary) ; Cyclophosphamide; Fludarabine
Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma
Focus Adverse reactions; First in man; Therapeutic Use

04 Jun 2024 Results (n=6) assessing safety of ET-901 in patients with r/r B-NHL presented at the 60th Annual Meeting of the American Society of Clinical Oncology
07 Sep 2023 Planned number of patients changed from 18 to 30.
07 Sep 2023 Status changed from not yet recruiting to recruiting.

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