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ToPCourT: A Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer (TNBC)

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Trial Profile

ToPCourT: A Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer (TNBC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Gemcitabine (Primary) ; Pembrolizumab (Primary) ; Trilaciclib (Primary)
  • Indications Advanced breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use
  • Acronyms ToPCourT

Most Recent Events

  • 20 Oct 2025 Status changed from recruiting to active, no longer recruiting.
  • 17 Jan 2024 Status changed from not yet recruiting to recruiting.
  • 05 Jan 2024 Planned initiation date changed from 1 Dec 2023 to 1 Jan 2024.

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