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A Phase I/II Clinical Study to Evaluate the Safety and Efficacy of RC118 in Combination with Toripalimab / RC148 for Patients with Claudin 18.2-Positive, Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

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Trial Profile

A Phase I/II Clinical Study to Evaluate the Safety and Efficacy of RC118 in Combination with Toripalimab / RC148 for Patients with Claudin 18.2-Positive, Locally Advanced Unresectable or Metastatic Malignant Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 Feb 2025

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At a glance

  • Drugs RC 118 (Primary) ; Toripalimab (Primary)
  • Indications Cholangiocarcinoma; Gastric cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors RemeGen

Most Recent Events

  • 29 Jan 2025 Arms decreased from 6 to 2. Primary endpoints amended.
  • 29 Jan 2025 Planned number of patients changed from 64 to 48.
  • 19 Sep 2023 New trial record

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