Trial Profile

A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Tozorakimab in Participants With Symptomatic Chronic Obstructive Pulmonary Disease (COPD) With a History of COPD Exacerbations (MIRANDA)

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 28 Apr 2026

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At a glance

20 Apr 2026 According to AstraZeneca media release, data will be submitted to regulatory authorities and shared with the scientific community at an upcoming medical meeting.
20 Apr 2026 According to AstraZeneca media release, Frank Sciurba is a Chief Investigator of LUNA programme. This LUNA programme includes OBERON, TITANIA, MIRANDA and PROSPERO.
20 Apr 2026 Primary endpoint has been met. (Annualized rate of moderate to severe COPD exacerbations in participants who are former smokers.)

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