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A Phase 3, Randomized, Double-blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer (INTerpath-002)

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Trial Profile

A Phase 3, Randomized, Double-blind, Placebo- and Active-Comparator-Controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With Resected Stage II, IIIA, IIIB (N2) Non-small Cell Lung Cancer (INTerpath-002)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 26 Jun 2025

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At a glance

  • Drugs Intismeran autogene (Primary) ; Pembrolizumab (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms INTerpath-002
  • Sponsors Merck & Co

Most Recent Events

  • 04 Jun 2024 Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
  • 04 Jun 2024 The results was presented and published in the Proceedings of the American Association for Cancer Research Annual Meeting 2024.
  • 22 May 2024 According to a Moderna Inc. media release, abstracts on mRNA-4157 (V940) from this trial, have been accepted for presentation at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which will be held May 31 - June 4 in Chicago, IL.

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