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A Phase II, randomised, open-label study evaluating the safety and efficacy of magrolimab in combination with venetoclax and azacitidine versus intensive chemotherapy in fit adults with high risk newly diagnosed acute myeloid leukaemia

Trial Profile

A Phase II, randomised, open-label study evaluating the safety and efficacy of magrolimab in combination with venetoclax and azacitidine versus intensive chemotherapy in fit adults with high risk newly diagnosed acute myeloid leukaemia

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 29 Feb 2024

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At a glance

  • Drugs Azacitidine (Primary) ; Magrolimab (Primary) ; Venetoclax (Primary) ; Cytarabine/daunorubicin; Fludarabine; Gemtuzumab ozogamicin; Granulocyte colony-stimulating factors; Idarubicin
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms ACT-AML-101
  • Most Recent Events

    • 27 Feb 2024 Status changed from recruiting to discontinued.
    • 20 Sep 2023 New trial record

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