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An Open Label Phase 2a Ascending Multiple Dose Safety, Efficacy, and Pharmacokinetic Study of HBI-002 Carbon Monoxide Oral Liquid Drug Product in Adolescents and Adults With Sickle Cell Disease

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Trial Profile

An Open Label Phase 2a Ascending Multiple Dose Safety, Efficacy, and Pharmacokinetic Study of HBI-002 Carbon Monoxide Oral Liquid Drug Product in Adolescents and Adults With Sickle Cell Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Aug 2026

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At a glance

  • Drugs Carbon monoxide (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions
  • Sponsors Hillhurst Biopharmaceuticals

Most Recent Events

  • 06 Aug 2026 Status changed from recruiting to completed.
  • 08 Jan 2026 Planned End Date changed from 31 Dec 2025 to 30 Jun 2026.
  • 08 Jan 2026 Planned primary completion date changed from 31 Aug 2025 to 31 Mar 2026.

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