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An Open Label Phase 2a Ascending Multiple Dose Safety, Efficacy, and Pharmacokinetic Study of HBI-002 Carbon Monoxide Oral Liquid Drug Product in Adolescents and Adults With Sickle Cell Disease

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Trial Profile

An Open Label Phase 2a Ascending Multiple Dose Safety, Efficacy, and Pharmacokinetic Study of HBI-002 Carbon Monoxide Oral Liquid Drug Product in Adolescents and Adults With Sickle Cell Disease

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 03 Jun 2025

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At a glance

  • Drugs Carbon monoxide (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions
  • Sponsors Hillhurst Biopharmaceuticals

Most Recent Events

  • 29 May 2025 Planned number of patients changed from 8 to 9.
  • 29 May 2025 Planned End Date changed from 1 Dec 2025 to 31 Dec 2025.
  • 29 May 2025 Planned primary completion date changed from 30 Jun 2025 to 31 Aug 2025.

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