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A Phase IV, Longitudinal, Observational Study Examining Real-World Outcomes of Non-Hormonal Pharmacotherapies Among Individuals Treated for Bothersome Vasomotor Symptoms

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Trial Profile

A Phase IV, Longitudinal, Observational Study Examining Real-World Outcomes of Non-Hormonal Pharmacotherapies Among Individuals Treated for Bothersome Vasomotor Symptoms

Status: Active, no longer recruiting
Phase of Trial: Phase IV

Latest Information Update: 23 Jul 2025

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At a glance

  • Drugs Fezolinetant (Primary) ; Citalopram; Clonidine; Desvenlafaxine; Escitalopram; Gabapentin; Oxybutynin; Paroxetine; Pregabalin; Serotonin uptake inhibitors; Venlafaxine
  • Indications Vasomotor symptoms
  • Focus Therapeutic Use
  • Acronyms OPTION-VMS
  • Sponsors Astellas Pharma Global Development

Most Recent Events

  • 11 Jun 2025 Status changed from recruiting to active, no longer recruiting.
  • 18 Jul 2024 Planned End Date changed from 30 Sep 2025 to 30 Nov 2026.
  • 18 Jul 2024 Planned primary completion date changed from 30 Sep 2025 to 28 Feb 2026.

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