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A Window of Opportunity Trial Evaluating the Oral TGF-beta Receptor I Inhibitor Vactosertib in Patients Undergoing Standard of Care Chemoradiotherapy for Locally Advanced Esophageal Adenocarcinoma

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A Window of Opportunity Trial Evaluating the Oral TGF-beta Receptor I Inhibitor Vactosertib in Patients Undergoing Standard of Care Chemoradiotherapy for Locally Advanced Esophageal Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Mar 2025

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At a glance

  • Drugs Vactosertib (Primary) ; Carboplatin; Paclitaxel
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 28 Nov 2024 Planned initiation date (estimated date of first participant enrollment) changed from 1 Oct 2024 to 1 Jan 2025.
    • 28 Nov 2024 Status changed from not yet recruiting to recruiting.
    • 10 May 2024 Planned initiation date changed from 1 Apr 2024 to 1 Oct 2024.

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