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First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

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Trial Profile

First-In-Human Study of STX-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 28 Apr 2025

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At a glance

  • Drugs STX-721 (Primary)
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; First in man; Pharmacokinetics; Therapeutic Use
  • Sponsors Antares Pharma; Scorpion Therapeutics

Most Recent Events

  • 23 Apr 2025 Planned number of patients changed from 120 to 185.
  • 31 Oct 2023 Planned End Date changed from 1 May 2028 to 1 Jun 2028.
  • 31 Oct 2023 Planned primary completion date changed from 17 Jul 2026 to 1 Jun 2027.

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