Implementing Geriatric Assessment for Dose Optimization of CDK 4/6-inhibitors in Older Breast Cancer Patients - a Pragmatic Randomized-controlled Trial (IMPORTANT Trial)
Latest Information Update: 17 Mar 2025
At a glance
- Drugs Abemaciclib (Primary) ; Anastrozole (Primary) ; Exemestane (Primary) ; Fulvestrant (Primary) ; Letrozole (Primary) ; Palbociclib (Primary) ; Ribociclib (Primary)
- Indications Advanced breast cancer; HER2 negative breast cancer
- Focus Therapeutic Use
- Acronyms IMPORTANT
Most Recent Events
- 13 Dec 2024 Trial design presented at the 47th Annual San Antonio Breast Cancer Symposium
- 19 Nov 2024 Planned End Date changed from 1 Apr 2031 to 31 May 2029.
- 19 Nov 2024 Planned primary completion date changed from 1 Apr 2028 to 31 Oct 2028.