A Phase 2, Partially-blinded, Randomised Trial Assessing the Safety and Efficacy of TBAJ-876 or Bedaquiline, in Combination with Pretomanid and Linezolid in Adult Participants with Newly Diagnosed, Drug-sensitive, Smear-positive Pulmonary Tuberculosis
Latest Information Update: 21 Feb 2025
At a glance
- Drugs Linezolid (Primary) ; Pretomanid (Primary) ; TBAJ-876 (Primary) ; Bedaquiline; Isoniazid/rifampicin; Rifampicin/isoniazid/pyrazinamide/ethambutol
- Indications Pulmonary tuberculosis
- Focus Therapeutic Use
- Sponsors Global Alliance for TB Drug Development
- 19 Sep 2024 Planned primary completion date changed from 1 Feb 2025 to 1 Jan 2025.
- 19 Sep 2024 Status changed from recruiting to active, no longer recruiting.
- 05 Mar 2024 Planned primary completion date changed from 1 Jan 2025 to 1 Feb 2025.