Trial Profile

A Phase 1 Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of GEN1042 Monotherapy and in Combination With Pembrolizumab ± Chemotherapy in Japanese Subjects With Malignant Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 21 Jan 2026

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At a glance

Drugs GEN 1042 (Primary) ; Pembrolizumab (Primary) ; Carboplatin; Cisplatin; Fluorouracil
Indications Head and neck cancer; Non-small cell lung cancer; Solid tumours; Squamous cell cancer
Focus Adverse reactions
Sponsors Genmab

06 Jan 2026 Planned End Date changed from 26 Dec 2026 to 28 Nov 2026.
06 Jan 2026 Planned primary completion date changed from 26 Mar 2026 to 28 Nov 2026.
15 Jun 2025 Status changed from recruiting to active, no longer recruiting.

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