Trial Profile

Phase 1, Dose Escalation, Safety, Tolerability, and Pharmacokinetic Study of SR-8541A (ENPP1 Inhibitor) Administered Orally as Monotherapy or in Combination With Checkpoint Inhibitors in Subjects With Advanced/Metastatic Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 16 Jun 2025

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At a glance

12 Mar 2025 Treatments section is updated to include immune-checkpoint inhibitors (nivolumab/pembrolizumab) also to be studied in combination with SR-8541A.
12 Mar 2025 Planned number of patients changed from 18 to 25.
12 Mar 2025 Planned End Date changed from 1 Aug 2024 to 1 Dec 2025.

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