Trial Profile

A Three-Part Phase 1 Study to Evaluate the Potential Drug-Drug Interactions Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel-Ethinyl Estradiol-Containing Oral Contraceptives, and Carbamazepine in Healthy Adult Participants

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 21 May 2024

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At a glance

Drugs Carbamazepine (Primary) ; Ethinylestradiol/levonorgestrel (Primary) ; Metformin (Primary) ; Rosuvastatin (Primary) ; Vemircopan (Primary)
Indications Autoimmune disorders; IgA nephropathy; Lupus nephritis; Myasthenia gravis; Paroxysmal nocturnal haemoglobinuria
Focus Pharmacokinetics
Sponsors Alexion AstraZeneca Rare Disease

14 May 2024 Status changed from recruiting to completed.
07 Mar 2024 Planned End Date changed from 18 Mar 2024 to 22 Mar 2024.
07 Mar 2024 Planned primary completion date changed from 18 Mar 2024 to 22 Mar 2024.

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