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A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

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Trial Profile

A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Aug 2025

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At a glance

  • Drugs Icotrokinra (Primary)
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms ICONIC-TOTAL
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 21 Jul 2025 According to Johnson & Johnson Media Release, company announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking the first approval of icotrokinra, a first-in-class investigational targeted oral peptide that selectively blocks the IL-23 receptor for the treatment of adults and pediatric patients 12 years of age and older with moderate to severe plaque psoriasis (PsO).
  • 09 May 2025 According to Johnson & Johnson Media Release, data from this study were presented at the 2025 American Academy of Dermatology Annual Meeting
  • 09 May 2025 According to Johnson & Johnson Media Release, data from this study were presented at presented at the 2025 Society for Investigative Dermatology (SID) Annual Meeting.

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