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A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

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Trial Profile

A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 20 Nov 2025

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At a glance

  • Drugs Icotrokinra (Primary)
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms ICONIC-TOTAL
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 24 Oct 2025 According to Johnson & Johnson Media Release, Edward (Ted) Lain, MD, MBA Executive Director of the Austin Institute for Clinical Research in Austin, Texas, and study investigator.
  • 24 Oct 2025 Results presented in the Johnson & Johnson Media Release.
  • 11 Sep 2025 According to Johnson & Johnson Media Release, long-term data from the ICONIC development programme, including at least 52-weeks of treatment for ICONIC-LEAD and ICONIC-TOTAL, and results from a randomised withdrawal analysis evaluating the durability of response, are being prepared for presentation at a future medical meeting.

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