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A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

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Trial Profile

A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 11 Sep 2026

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At a glance

  • Drugs Icotrokinra (Primary)
  • Indications Plaque psoriasis
  • Focus Registrational; Therapeutic Use
  • Acronyms ICONIC-TOTAL
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 18 Mar 2026 According to Johnson & Johnson Media Release, company announced today that the U.S. Food and Drug Administration (FDA) has approved ICOTYDE™ (icotrokinra), an interleukin-23 (IL-23) receptor antagonist for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age and older who weigh at least 40 kg who are candidates for systemic therapy or phototherapy.
  • 20 Jan 2026 Planned End Date changed from 10 Jun 2027 to 17 Feb 2027.
  • 24 Oct 2025 According to Johnson & Johnson Media Release, Edward (Ted) Lain, MD, MBA Executive Director of the Austin Institute for Clinical Research in Austin, Texas, and study investigator.

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