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Phase 0/1 Study of the Safety and Tolerability of 177Lu-RAD204, a Lutetium-177 Radiolabelled Single Domain Antibody Against Programmed Cell Death-Ligand 1 in Patients with Metastatic Non-small Cell Lung Cancer

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Trial Profile

Phase 0/1 Study of the Safety and Tolerability of 177Lu-RAD204, a Lutetium-177 Radiolabelled Single Domain Antibody Against Programmed Cell Death-Ligand 1 in Patients with Metastatic Non-small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Mar 2025

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At a glance

  • Drugs RAD 204 (Primary)
  • Indications Advanced breast cancer; Carcinoma; Endometrial cancer; Head and neck cancer; Male breast cancer; Malignant melanoma; Non-small cell lung cancer; Skin cancer; Small cell lung cancer; Squamous cell cancer; Triple negative breast cancer
  • Focus Adverse reactions; First in man; Pharmacokinetics; Therapeutic Use
  • Sponsors Radiopharm Theranostics

    • Most Recent Events

    • 21 Mar 2025 The protocol has been amended to change in phase with change in Patient Inclusion Criteria now SCLC, TNBC, cutaneous melanoma, HNSCC, and endometrial cancer will be recruited.
    • 21 May 2024 Planned initiation date (estimated date of first participant enrollment) changed from 1 Mar 2024 to 1 May 2024.
    • 10 Oct 2023 New trial record

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