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A Phase 3, Randomised, Double-blind, Parallel-group, Event-driven, Cardiovascular Safety Study With BI 456906 Administered Subcutaneously Compared With Placebo in Participants With Overweight or Obesity With Established Cardiovascular Disease (CVD) or Chronic Kidney Disease, and/or at Least Two Weight-related Complications or Risk Factors for CVD

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Trial Profile

A Phase 3, Randomised, Double-blind, Parallel-group, Event-driven, Cardiovascular Safety Study With BI 456906 Administered Subcutaneously Compared With Placebo in Participants With Overweight or Obesity With Established Cardiovascular Disease (CVD) or Chronic Kidney Disease, and/or at Least Two Weight-related Complications or Risk Factors for CVD

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 01 Jul 2025

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At a glance

  • Drugs Survodutide (Primary)
  • Indications Obesity
  • Focus Adverse reactions; Registrational
  • Acronyms SYNCHRONIZE-CVOT; SYNCHRONIZE™ - CVOT
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 10 Mar 2025 Status changed from recruiting to active, no longer recruiting.
  • 07 Feb 2025 Planned End Date changed from 2 Apr 2026 to 13 Jul 2026.
  • 13 Sep 2024 Trial design presented at the 60th Annual Meeting of the European Association for the Study of Diabetes

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