Trial Profile

An Open-label, Phase I Trial With Expansion Cohort of Nab-Paclitaxel + Gemcitabine + Cisplatin + Botensilimab (AGEN1811) + Balsilimab (AGEN2034) + Chloroquine + Celecoxib in Patients With Previously Untreated Metastatic Pancreatic Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 16 Jan 2026

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At a glance

Drugs Aspirin (Primary) ; Balstilimab (Primary) ; Botensilimab (Primary) ; Celecoxib (Primary) ; Chloroquine (Primary) ; Cisplatin (Primary) ; Famotidine (Primary) ; Gemcitabine (Primary) ; Paclitaxel (Primary)
Indications Adenocarcinoma; Pancreatic cancer; Pancreatic ductal carcinoma
Focus Adverse reactions
Acronyms The Seven Trial

12 Jan 2026 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
12 Jan 2026 Planned primary completion date changed from 1 Jun 2025 to 1 Jun 2026.
12 Jan 2026 Status changed from recruiting to active, no longer recruiting.

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