Trial Profile

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study of TPST-1120 in Combination With Atezolizumab Plus Bevacizumab Compared With Placebo Plus Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic Hepatocellular Carcinoma (HCC) Not Previously Treated With Systemic Therapy

Status: Not yet recruiting

Phase of Trial: Phase III

Latest Information Update: 31 Mar 2025

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At a glance

27 Mar 2025 According to a Tempest media release, company announced positive feedback from the end-of-Phase 2 meeting with the FDA for amezalpat in combination with atezolizumab and bevacizumab to treat first-line unresectable or metastatic HCC.
12 Nov 2024 According to a Tempest media release, company received a Study May Proceed letter from the U.S. Food and Drug Administration (FDA) to evaluate amezalpat (TPST-1120) in combination with atezolizumab and bevacizumab.
08 Nov 2024 Status changed from planning to not yet recruiting.

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