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A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects With Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy

Trial Profile

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects With Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 10 Apr 2026

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At a glance

  • Drugs Upadacitinib (Primary)
  • Indications Vitiligo
  • Focus Registrational; Therapeutic Use
  • Acronyms Viti-Up
  • Sponsors AbbVie

Most Recent Events

  • 27 Mar 2026 According to an Abbvie media release, data from this trial will be presented at the 2026 American Academy of Dermatology (AAD) Annual Meeting, March 27 to 31 in Denver, Colorado.
  • 03 Feb 2026 According to an AbbVie media release, company has submitted applications to the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) for a new indication for upadacitinib, supported by data from the phase 3 Viti-Up clinical studies.
  • 29 Oct 2025 Primary endpoint has been met (Percentage of Participants Achieving Facial-Vitiligo Area Scoring Index (F-VASI) 75 ( 75% Improvement in F-VASI From Baseline)), according to AbbVie media release.

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