A Phase 3, Randomized, Double-blinded, Placebo-controlled, Multicenter Study to Evaluate Efficacy and Safety of ALXN1850 (Recombinant Alkaline Phosphatase) Administered Subcutaneously in Adolescent (12 to < 18 Years of Age) and Adult Participants With Hypophosphatasia Who Have Not Previously Been Treated With Asfotase Alfa
Latest Information Update: 31 May 2025
At a glance
- Drugs Efzimfotase alfa (Primary)
- Indications Hypophosphatasia
- Focus Registrational; Therapeutic Use
- Acronyms HICKORY
- Sponsors Alexion AstraZeneca Rare Disease
Most Recent Events
- 15 Apr 2025 Planned End Date changed from 29 Mar 2028 to 29 May 2029.
- 20 Mar 2025 Planned primary completion date changed from 6 Aug 2025 to 11 Jul 2025.
- 20 Feb 2025 Planned primary completion date changed from 24 Jul 2025 to 6 Aug 2025.