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First-in-human Safety Study of Hypoimmune Pancreatic Islet Transplantation in Adult Subjects With Type 1 Diabetes

Trial Profile

First-in-human Safety Study of Hypoimmune Pancreatic Islet Transplantation in Adult Subjects With Type 1 Diabetes

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Mar 2025

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At a glance

  • Drugs UP 421 (Primary)
  • Indications Type 1 diabetes mellitus
  • Focus Adverse reactions; First in man
  • Sponsors Sana Biotechnology

Most Recent Events

  • 17 Mar 2025 According to a Sana Biotechnology media release, company expects to report additional data from this study, including longer-term follow-up, as the year progresses in a peer-reviewed publication and/or at scientific conferences. The preliminary 12-week results remain subject to source data verification.
  • 07 Jan 2025 According to a Sana Biotechnology media release, company announced results of the study at four weeks after cell transplantation demonstrate the survival and function of pancreatic beta cells
  • 07 Jan 2025 Results published in the Sana Biotechnology media release

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