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A Randomized Phase 2b/Phase 3 Study of the TGF-β2 Targeting Antisense Oligonucleotide OT-101 in Combination With mFOLFIRINOX Compared With mFOLFIRINOX Alone in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

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A Randomized Phase 2b/Phase 3 Study of the TGF-β2 Targeting Antisense Oligonucleotide OT-101 in Combination With mFOLFIRINOX Compared With mFOLFIRINOX Alone in Patients With Advanced and Unresectable or Metastatic Pancreatic Cancer

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 16 Aug 2024

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At a glance

  • Drugs Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Trabedersen (Primary)
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use
  • Acronyms STOP-PC
  • Sponsors Oncotelic Therapeutics

    • Most Recent Events

    • 13 Mar 2024 Planned number of patients changed from 468 to 455.
    • 13 Mar 2024 Planned initiation date changed from 1 Dec 2023 to 1 May 2024.
    • 04 Mar 2024 Status changed from not yet recruiting to recruiting, according to an Oncotelic Therapeutics media release. The company invites participation in this STOP-PC clinical trial which is now open for recruitment.

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