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A Phase III, Open-Label, Multicenter Randomized Study Evaluating Glofitamab as a Single Agent Versus Investigator's Choice in Patients With Relapsed/Refractory Mantle Cell Lymphoma

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Trial Profile

A Phase III, Open-Label, Multicenter Randomized Study Evaluating Glofitamab as a Single Agent Versus Investigator's Choice in Patients With Relapsed/Refractory Mantle Cell Lymphoma

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 09 Feb 2026

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At a glance

  • Drugs Glofitamab (Primary) ; Bendamustine; Lenalidomide; Obinutuzumab; Rituximab; Tocilizumab
  • Indications Mantle-cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms GLOBRYTE
  • Sponsors Roche

Most Recent Events

  • 03 Feb 2026 Planned End Date changed from 30 Sep 2027 to 31 Mar 2028.
  • 03 Feb 2026 Planned primary completion date changed from 26 Feb 2027 to 31 Aug 2027.
  • 03 Aug 2025 Planned End Date changed from 30 Jun 2027 to 30 Sep 2027.

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