A Phase I/II Open-Label Study to Evaluate the Safety, Cellular Kinetics and Efficacy of AZD5851, a Chimeric Antigen Receptor T-Cell (CAR-T) Therapy Directed Against GPC3 in Adult Participants With Advanced/Recurrent Hepatocellular Carcinoma: ATHENA
Latest Information Update: 29 Apr 2025
At a glance
- Drugs AZD-5851 (Primary) ; Cyclophosphamide; Fludarabine
- Indications Liver cancer
- Focus Adverse reactions; First in man
- Acronyms ATHENA
- Sponsors AstraZeneca
Most Recent Events
- 30 Oct 2024 Planned number of patients changed from 84 to 94.
- 04 Jun 2024 Trial design presented at the 60th Annual Meeting of the American Society of Clinical Oncology
- 22 Dec 2023 Planned End Date changed from 4 Jan 2028 to 13 Dec 2027.