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A Phase 1/2 Study of OR502 Alone and in Combination With Other Anti-cancer Agents in Subjects With Advanced Malignancies

Trial Profile

A Phase 1/2 Study of OR502 Alone and in Combination With Other Anti-cancer Agents in Subjects With Advanced Malignancies

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 16 Jun 2025

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At a glance

  • Drugs Cemiplimab (Primary) ; OR-502 (Primary)
  • Indications Carcinoma; Malignant melanoma; Non-small cell lung cancer; Ovarian cancer; Sarcoma; Skin cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man
  • Sponsors OncoResponse

Most Recent Events

  • 30 Apr 2025 Results reporting pharmacokinetic (PK) and receptor occupancy (RO) data from a phase 1 study dose escalation cohorts in patients with refractory solid tumors presented at the 116th Annual Meeting of the American Association for Cancer Research.
  • 30 Apr 2025 Trial design presented at the 116th Annual Meeting of the American Association for Cancer Research.
  • 07 Nov 2024 Results presented in the OncoResponse media release.

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