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Phase 1b Dose Expansion Study of NXC-201 for the Treatment of Patients with Relapsed or Refractory AL Amyloidosis

Trial Profile

Phase 1b Dose Expansion Study of NXC-201 for the Treatment of Patients with Relapsed or Refractory AL Amyloidosis

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Jul 2025

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At a glance

  • Drugs NXC 201 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Amyloid light-chain amyloidosis
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms NEXICART-2
  • Sponsors Nexcella

Most Recent Events

  • 11 Jul 2025 According to an Immix Biopharma media release, the company is on a track for first Biologics License Application (BLA) submission to FDA,supported by data from this trial.
  • 07 Jul 2025 According to an Immix Biopharma media release, a webcast of the Company's Key Opinion Leader (KOL) event was held on 3 June 2025, to discuss the NXC-201 ASCO 2025 interim results.
  • 07 Jul 2025 According to an Immix Biopharma media release, for the progress of this clinical trial, number of site are increased to include 18 clinical trial sites in US. The trial is moving faster than expected and additional new sites further accelerate the path to BLA submission for FDA approval.

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