Trial Profile

Single Arm Phase II Clinical Trial of Recombinant Humanized Anti PD-1 Monoclonal Antibody and FOLFOXIRI Regimen Combined With Preoperative Intensity Modulated Radiation Therapy as the Total Neoadjuvant Treatment for pMMR Locally Advanced Low Rectal Cancer

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 04 Jun 2025

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At a glance

Drugs Capecitabine (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Serplulimab (Primary)
Indications Adenocarcinoma; Rectal cancer
Focus Therapeutic Use

01 Jun 2025 According to a Shanghai Henlius Biotech media release, data from this study presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
27 Oct 2023 New trial record

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