Trial Profile

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 11 Aug 2025

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At a glance

Drugs AFNT 211 (Primary)
Indications Adenocarcinoma; Carcinoma; Colorectal cancer; Non-small cell lung cancer; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions; First in man
Sponsors Affini-T Therapeutics

Most Recent Events

29 Jul 2025 Status changed from recruiting to active, no longer recruiting.
30 Apr 2025 Trial design presented at the 116th Annual Meeting of the American Association for Cancer Research.
06 Nov 2024 According to an Affini-T Therapeutics media release, the company will present a Trial-In-Progress poster at the Society for Immunotherapy of Cancer (SITC) 39th Annual Meeting held in Houston, TX, November 6-10.

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