A Phase I/II study of mezigdomide in combination with selinexor in patients with relapsed/refractory multiple myeloma progressing after T-cell Immunotherapies

Status: Planning

Phase of Trial: Phase I/II

Latest Information Update: 01 Nov 2023

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At a glance

01 Nov 2023 New trial record
30 Oct 2023 According to a Karyopharm Therapeutics media release, company planning to initiate the trial in the first half of 2024.
30 Oct 2023 According to a Karyopharm Therapeutics media release, company has entered into a clinical trial collaboration and supply agreement with Bristol-Myers Squibb (NYSE: BMY) to evaluate the company's proprietary investigational cereblon E3 ligase modulator (CELMoD™) agent mezigdomide in combination with Karyopharm's selinexor, an approved first-in-class inhibitor of Exportin 1 (XPO1), plus dexamethasone in patients with relapsed/refractory multiple myeloma.

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