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A Phase 2/3, Randomized Study to Evaluate the Dose Optimization, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab in Subjects With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Who Have Not Previously Received Systemic Treatment

Trial Profile

A Phase 2/3, Randomized Study to Evaluate the Dose Optimization, Safety, and Efficacy of Livmoniplimab in Combination With Budigalimab in Subjects With Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) Who Have Not Previously Received Systemic Treatment

Status: Recruiting
Phase of Trial: Phase II/III

Latest Information Update: 18 Mar 2025

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At a glance

  • Drugs Budigalimab (Primary) ; Livmoniplimab (Primary) ; Atezolizumab; Bevacizumab; Durvalumab; Tremelimumab
  • Indications Carcinoma; Liver cancer
  • Focus Therapeutic Use
  • Acronyms LIVIGNO-2
  • Sponsors AbbVie
  • Most Recent Events

    • 12 Dec 2024 Planned End Date changed from 6 Sep 2030 to 1 Sep 2030.
    • 12 Dec 2024 Planned primary completion date changed from 6 Sep 2030 to 1 Sep 2030.
    • 29 May 2024 Trial design discussed at 60th Annual Meeting of the American Society of Clinical Oncology

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