Trial Profile

A Pilot Study on the Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 Diabetes (COCONUT)

Status: Completed

Phase of Trial: Phase IV

Latest Information Update: 25 Sep 2024

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At a glance

Drugs Exenatide (Primary) ; Glucagon (Primary)
Indications Type 2 diabetes mellitus
Focus Therapeutic Use
Acronyms COCONUT

Most Recent Events

19 Sep 2024 Status changed from recruiting to completed.
03 Nov 2023 New trial record
06 Oct 2023 Results (n=8) assessing the effects of dual GLP-1 and glucagon RA on myocardial function and whether these effects correlated with myocardial glucose uptake (MGU) in overweight individuals with T2DM, using [18F]FDG PET/MRI presented at the 59th Annual Meeting of the European Association for the Study of Diabetes

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