Trial Profile

A First-in-Human, Open-label, Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of ENV-501 in Patients With Advanced-Stage, Relapsed/Refractory HER3-Expressing Solid Tumors

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 08 May 2025

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At a glance

Drugs HMBD 501
Indications Breast cancer; Malignant melanoma; Non-small cell lung cancer; Solid tumours
Focus Adverse reactions; First in man; Therapeutic Use
Sponsors Endeavor BioMedicines

06 May 2025 Status changed from planning to recruiting.
06 Nov 2023 New trial record
02 Nov 2023 According to an Endeavor BioMedicines media release, the first-in-human trial of HMBD 501 will begin clinical development in 2024 for the treatment of multiple solid tumors.

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