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A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of Saruparib (AZD5305) in Combination With Physician's Choice New Hormonal Agents in Patients With HRRm and Non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01)

Trial Profile

A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of Saruparib (AZD5305) in Combination With Physician's Choice New Hormonal Agents in Patients With HRRm and Non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 17 May 2025

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At a glance

  • Drugs Saruparib (Primary) ; Abiraterone acetate; Darolutamide; Enzalutamide
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms EvoPAR-Prostate01
  • Sponsors AstraZeneca

Most Recent Events

  • 04 Jun 2024 Trial design from this study were presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
  • 07 Mar 2024 Planned End Date changed from 23 Apr 2031 to 30 Apr 2031.
  • 29 Jan 2024 Planned End Date changed from 1 May 2031 to 23 Apr 2031.

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