Trial Profile

An Observational Study in Patients With Unresectable Hepatocellular Carcinoma (uHCC) Following Treatment With Atezolizumab Plus Bevacizumab (AB) or With Another Approved Immuno-oncology Immune Checkpoint Inhibitor Combination in First-line

Status: Recruiting

Phase of Trial: Phase IV

Latest Information Update: 17 Mar 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Durvalumab (Primary) ; Tremelimumab (Primary)
Indications Liver cancer
Focus Therapeutic Use
Acronyms REFINE-IO
Sponsors Bayer

12 Dec 2023 Planned primary completion date changed from 10 Nov 2026 to 27 Nov 2026.
12 Dec 2023 Status changed from not yet recruiting to recruiting.
17 Nov 2023 Planned initiation date changed from 10 Nov 2023 to 20 Nov 2023.

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