Trial Profile

A Phase 1b, Open-Label, Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 With Panitumumab in Patients With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Status: Discontinued

Phase of Trial: Phase I

Latest Information Update: 23 Apr 2025

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At a glance

Drugs Brimarafenib (Primary) ; Panitumumab (Primary)
Indications Colorectal cancer; Pancreatic cancer; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions; Therapeutic Use
Sponsors MapKure

20 Apr 2025 Status changed from recruiting to discontinued.
20 Mar 2024 Status changed from not yet recruiting to recruiting.
28 Feb 2024 According to SpringWorks Therapeutics media release, the company will initiate a Phase 1b trial in the first quarter of 2024.

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